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The BIOFIRE System and Your Immune System The BIOFIRE System provides syndromic infectious disease testing, empowering healthcare professionals to choose the right test the first time. Patients benefit from faster diagnosis and more targeted therapy. Clinicians benefit from improved stewardship of antibiotics. Labs improve efficiency and cost savings. The BioFire Pneumonia Plus Panel (PN panel) analyzes native sputum (including mini-BAL) and endotracheal lavage and bronchoalveolar slurries (including mini BAL) for 33 clinically significant pathogens and resistance genes to antimicrobials in an hour. Respiratory The burning of biomass, such as wood, plants and other organic materials produces gaseous pollution and fine particles that negatively affect the respiratory system. bioethanol fuel fires fireplacesandstove.com can exacerbate the negative effects of forest fires on the health of humans. In the United States, wildfire smoke has been linked to hospitalizations for respiratory diseases, such as asthma, COPD and lung cancer. This type of pollution to the air also increases the risk of developing cardiovascular diseases and is a major cause of the burden on disease among the most vulnerable populations. Wildfires caused unhealthy levels of air pollution in many communities during the COVID-19 epidemic. The public health response has been limited to a communication campaign about symptom management. This knowledge gap is alarming, due to the fact that smoking cigarettes and other sources of poor quality air can lead to health problems. Researchers are currently evaluating the best methods to safeguard the public's health in future events of this kind. NIH is funding research into this crucial public health issue through the BLUE CORAL study and its successor FIRE CORAL. For the first time that a prospective study is conducted, it will examine the long-term effects of exposure to smoke from wildfires or other sources. FIRE CORAL is recruiting adult participants who are hospitalized for the COVID-19 index episode who speak English or Spanish and are not pregnant. The Fire Coral protocol includes a battery in-person assessments that objectively measure the pulmonary function testing, lung imaging and functional assessment. Smoke and other particles can cause or worsen chronic respiratory conditions such as emphysema, COPD, and pneumonia. A variety of steps can be taken to avoid or reduce the adverse health effects from short-term exposures to smoke, such as abstaining from outdoor activities when it is feasible and wearing the EPA's “N95” mask designed to catch fine particles. Smoking can also cause irritation to the eyes, throat and nose. To lessen the effects the lungs need to be flushed by drinking lots of water and taking medicines that reduce inflammation, like corticosteroids. Bloodstream Your bloodstream is at the forefront of fighting germs that invade your body. Dendritic cells are special cells, function as a call center for your fire department. They gather antigens from germs and release proteins to signal other white cells to fight off them. Circulating total white blood cell counts, differentials and band cells were boosted following firefighters' fire-fighting shifts, compared with levels after strenuous physical exertion without firefighting. Skin As the wildfires in California spewed smoke and ash into the air during winter and fall dermatologists were concerned about how that could affect the skin of people exposed to it. Maria Wei, a graduate student at University of California, Irvine, is studying how extreme fire pollution affects skin. Her research was published in Scientific Reports on April 22nd. The study of Wei shows that the temperature of the skin changes dependent on the amount of time the body is exposed. It can take as long as two hours for the skin of an individual to reach its “flash point”—the moment at which it begins to burn and then turns ashy. This is why it's crucial to avoid being near a fire or campfire, and why you should wear protective clothing when you are outside during a forest fire, or even an extremely hot day. While it's important to be aware of the dangers of wildfire-related pollution, there's no way to stop forest fires from occurring. Wei predicts that the number of people suffering from the consequences of wildfires will increase as climate change causes more and more forests to burn. This means that more people will need to wear hats and long sleeves and also thick moisturizers. Air pollution from wildfires can exacerbate atopic skin dermatitis, which is a condition that causes itchy skin for many people. She says that the particles in smoke can block pores, making atopic skin worse. Atopic dermatitis can also make people more sensitive to UV light. This can be made worse by smoke from wildfires. This makes people more likely to visit tanning salons, and it may cause the skin to get darker with less protection than they ought to. A treatment using ice and fire may help reduce atopic skin dermatitis symptoms however, it isn't advised for anyone who has an open wound or rash. This treatment is not recommended for people who have active acne, or if you're pregnant or nursing. The IS Clinical Fire & Ice Facial is offered at Novuskin Las Vegas' premier membership MedSpa is a result-driven, intensive facial that bridges between an easy facelift and a peel, without requiring downtime. It's designed to rejuvenate the skin, alleviate rosacea symptoms, decrease acne scarring, reduce wrinkles, and promote cell renewal. It's a fantastic treatment to give yourself an energizing glow. Infections The human body is a multi-faceted system of organs and tissues that work together to shield us from infections. Infections can be caused by microorganisms, such as bacteria, viruses and parasites that infect healthy cells, causing them to multiply in uncontrolled ways. Your immune system could react by exhibiting symptoms of illness. These symptoms could include a runny nose to an upset stomach and can also include an increase in fever, swelling of lymph glands or a skin rash. The severity of your symptoms may be affected by the nature of the infection, its location and even your temperature. Infections can spread in a variety of ways but the most prevalent are from person to person by droppings that hang in the air after coughing or sneezing. This is how bacterial diseases such as tuberculosis, strep and meningococcal illness and viral infections, such as the common cold and influenza are transmitted. Certain bacterial infections like skin infections or sexually transmitted diseases (STIs) such as gonorrhea or chlamydia are spread through direct contact with affected mucous or tissue surfaces, or indirectly by contaminated surfaces. Some bacterial infections are spread by insects, such as ticks, fleas or mosquitoes. Viruses and some parasites are small enough to get into your bloodstream and infect your cells, which can lead to serious diseases like the common cold and AIDS. Fungi can trigger skin conditions such as ringworm and athlete's foot, while others infect the respiratory tract and nervous system. The BioFire PN Panel uses our revolutionary FilmArray technology to detect a comprehensive list of pathogens that are involved in upper respiratory infections in sputum and bronchoalveolar lavage fluid samples. The kit comes with a reagent kit that contains all the chemistry necessary to perform reverse transcription, nested multiplex PCR and detection in one machine. It's an easy-to-use solution to help clinicians syndromicly identify and treat patients with different respiratory symptoms. The test has been granted an Emergency Use Authorization. It's available in bioMerieux CLIA medium and high-complex laboratories.